500 Participants Needed

Yoga for Scoliosis

(AIS Trial)

AH
GR
Overseen ByGabrielle Reichard, MA
Age: < 65
Sex: Any
Trial Phase: Academic
Sponsor: Johns Hopkins University
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial explores whether adding yoga to the usual care for adolescents with Adolescent Idiopathic Scoliosis (AIS) can improve their quality of life. AIS involves a spinal curve of more than 10 degrees and can lead to back pain, poor sleep, and depression. Participants will either continue their standard care, with or without a brace, or incorporate yoga sessions into their routine. The trial targets those with scoliosis and a spinal curve over 25 degrees who experience significant back pain. It aims to determine if yoga can reduce the need for medications and improve both physical and mental health. As an unphased trial, this study offers a unique opportunity to explore innovative care options that could enhance quality of life.

Will I have to stop taking my current medications?

The trial information does not specify whether you need to stop taking your current medications. It focuses on adding yoga to your existing treatment plan, so it's likely you can continue your current medications, but you should confirm with the trial coordinators.

What prior data suggests that this yoga protocol is safe for adolescents with scoliosis?

Research has shown that yoga can be a safe and beneficial activity for people with scoliosis. One study found that individuals with spine issues, including scoliosis, experienced positive results from regular yoga practice. Another study found that yoga reduced the spine's curve by an average of 4.60 degrees compared to traditional treatments.

Yoga is generally well-tolerated, and these studies reported no major safety concerns. The practice involves gentle, controlled movements, making it a low-risk option for many. However, as with any exercise, following advice from qualified instructors is crucial to ensure safety.12345

Why are researchers excited about this trial?

Unlike the standard scoliosis treatments that mainly involve braces or surgery, yoga offers a non-invasive, holistic approach that focuses on improving flexibility and muscle strength. Researchers are excited about yoga for scoliosis because it may enhance posture and spinal alignment through specific poses, potentially reducing pain and discomfort. This method is also accessible, as it can be done online, making it a convenient option for patients who prefer at-home treatment. Additionally, yoga promotes overall well-being, which can be an added benefit beyond the physical improvements.

What evidence suggests that this yoga protocol is effective for managing adolescent idiopathic scoliosis?

This trial will compare different approaches for managing scoliosis, including yoga and standard care. Research has shown that yoga can help manage scoliosis. One study found that after about 9 months of practicing yoga, certain spine curves improved by an average of 34.2%. Another study showed that yoga reduced the Cobb angle, which measures spine curvature, by an average of 4.60 degrees. A 16-week yoga program also significantly decreased the Cobb angle, leading to better posture and spine alignment. These findings suggest that yoga can help reduce spine curvature and improve posture in people with scoliosis. Participants in this trial will be randomized into different groups, including those practicing yoga with or without a brace, and those continuing with standard care.14567

Who Is on the Research Team?

PS

Paul Sponseller, MD

Principal Investigator

Johns Hopkins School of Medicine

Are You a Good Fit for This Trial?

This trial is for adolescents with a pronounced spinal curvature (Cobb angle over 25 degrees) and significant back pain, who are being treated non-surgically for Adolescent Idiopathic Scoliosis at JHH. It includes those undergoing physical therapy, both braced and unbraced patients.

Inclusion Criteria

I am either wearing a brace or not wearing a brace.
I have back pain from AIS and am eligible for physical therapy without surgery.
My spine curve is over 25 degrees and my pain score is more than 4.

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants are randomized into groups to receive either standard care or standard care with yoga. Yoga sessions are conducted online twice a week for 20 minutes.

6 months
Online sessions twice a week

Follow-up

Participants are monitored for pain, quality of life, and Cobb angle changes at 6 months and 1 year.

6 months
Assessments at 6 months and 1 year

Long-term Follow-up

Participants continue to be monitored for long-term outcomes and engagement.

1 year

What Are the Treatments Tested in This Trial?

Interventions

  • Yoga
Trial Overview The study tests the effectiveness of adding a structured yoga protocol to the standard care for managing AIS. Participants will be randomly assigned to either continue with their usual treatment or incorporate yoga into their regimen.
How Is the Trial Designed?
4Treatment groups
Active Control
Group I: Yoga BracedActive Control1 Intervention
Group II: Yoga - Not BracedActive Control1 Intervention
Group III: Braced - Standard of careActive Control1 Intervention
Group IV: Non Braced - Standard of careActive Control1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Johns Hopkins University

Lead Sponsor

Trials
2,366
Recruited
15,160,000+

Published Research Related to This Trial

A review of 12 relevant studies on exercise therapy for adolescent idiopathic scoliosis (AIS) found that while all studies supported its use, the evidence was of poor quality with significant methodological shortcomings.
Many studies reported small improvements in the curvature of the spine (Cobb angle) after exercise therapy, but these changes were not statistically robust and lacked long-term follow-up, indicating a need for better-designed research in this area.
Efficacy of exercise therapy for the treatment of adolescent idiopathic scoliosis: a review of the literature.Mordecai, SC., Dabke, HV.[2022]
A short-term Schroth exercise camp significantly improved trunk rotation angle, postural symmetry, trunk muscle endurance, and dynamic balance in 45 adolescents with idiopathic scoliosis after just 7 days of intensive corrective exercises.
Participants also reported better perceptions of cosmetic deformity and improved health-related quality of life, indicating that the Schroth method may be an effective intervention for managing symptoms of adolescent idiopathic scoliosis.
Effect of Short-Term 3-Dimensional Schroth Exercises In Adolescent Idiopathic Scoliosis: An Observational Study.Aktan, D., Erdoganoglu, Y.[2022]
A nonrandomized control trial involving 56 adolescents with idiopathic scoliosis showed that specific yoga poses significantly reduced the Cobb angles, indicating improvement in spinal curvature, with a mean change of -9.2 degrees in the treatment group compared to a deterioration of 5.4 degrees in the control group.
Patients receiving yoga treatment in-office experienced greater improvements (1.6 degrees/month) compared to those using telemedicine (0.72 degrees/month), suggesting that while both methods were beneficial, in-person sessions may lead to better adherence and outcomes.
Isometric Yoga-Like Maneuvers Improve Adolescent Idiopathic Scoliosis-A Nonrandomized Control Trial.Fishman, LM.[2022]

Citations

Exploring the Effectiveness of Hatha Yoga as a ...The results showed that after an average of 9.4 months of practice, there was an average improvement of 34.2% in the lumbar/thoracolumbar curves and 20.3% in ...
The effect of an exercise intervention on adolescent idiopathic ...Compared with conventional therapy, yoga reduced the average Cobb angle by 4.60 degrees and ranked first in the cumulative probability of ...
Effect of a 16-Week Yoga Program on Cobb's Angle in ...The current study suggests that a 16-week yoga exercise program can improve postural imbalances based on Cobb's angle in the spine, shoulder ...
(PDF) Effect of a 16-Week Yoga Program on Cobb's Angle ...RESULTS Following the 16-week program, Cobb's angle had significantly decreased from 10.50±4.26 to 7.05±3.37 (p<0.001). However, there were no ...
Yoga for Scoliosis (AIS Trial)A nonrandomized control trial involving 56 adolescents with idiopathic scoliosis showed that specific yoga poses significantly reduced the Cobb angles, ...
Is physical activity contraindicated for individuals with ...Nonsurgically treated scoliosis is not a contraindication to sports participation (grade D recommendation [3 level 5 studies8,19,28]).
Mental and physical outcomes of yoga participation in ...Likewise, participants with structural spinal conditions like lordosis, kyphosis, and scoliosis reported positive outcomes from regular yoga ...
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