tDCS + Cognitive Training for Breast Cancer Survivors
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial explores whether a device called transcranial direct current stimulation (tDCS) can improve memory in breast cancer survivors. The focus is on those who have experienced memory issues since completing chemotherapy. Participants will undergo cognitive training combined with tDCS to assess its effectiveness. Ideal candidates are breast cancer survivors who completed chemotherapy at least six months ago and are experiencing new memory problems. As an unphased trial, this study offers participants the chance to contribute to innovative research that could enhance memory recovery strategies for breast cancer survivors.
Will I have to stop taking my current medications?
The trial information does not specify whether you need to stop taking your current medications. It might be best to discuss this with the trial coordinators.
What prior data suggests that this device is safe for memory rehabilitation in breast cancer survivors?
Research shows that transcranial direct current stimulation (tDCS) is generally safe and easy to tolerate. Studies have found that tDCS is painless and simple to use. It has helped with attention problems and improved thinking skills in cancer survivors. Most people experience only mild side effects, if any, providing strong evidence that this treatment is safe for humans.12345
Why are researchers excited about this trial?
Researchers are excited about transcranial direct current stimulation (tDCS) combined with cognitive training for breast cancer survivors because it offers a non-invasive approach to potentially improve cognitive function, which can be affected by cancer treatments. Unlike traditional therapies that may focus on medication or surgery, tDCS uses gentle electrical currents to stimulate specific areas of the brain, which might enhance cognitive performance without the side effects associated with drugs. This technique also allows for targeted brain modulation, possibly leading to more personalized and effective cognitive rehabilitation.
What evidence suggests that tDCS is effective for memory rehabilitation in breast cancer survivors?
Research has shown that transcranial direct current stimulation (tDCS), which participants in this trial will receive alongside cognitive training, might improve thinking and memory in breast cancer survivors. Studies have found that tDCS is easy and comfortable for patients to use. It may also help with attention and memory issues. Some evidence suggests that when combined with brain exercises, tDCS could enhance skills like remembering words, holding information in mind, and thinking quickly. Although more research is needed, early results are promising for those experiencing cognitive issues related to cancer.12367
Who Is on the Research Team?
James Root, PhD
Principal Investigator
Memorial Sloan Kettering Cancer Center
Are You a Good Fit for This Trial?
This trial is for breast cancer survivors aged 40-65 who finished chemotherapy at least six months ago, have no current evidence of disease, and may or may not be on endocrine therapy. They should self-report memory or cognitive issues post-treatment and must understand English. Excluded are those with pacemakers, neurological illnesses, pregnancy/breastfeeding status, schizophrenia, bipolar disorder, untreated depression/anxiety, or a history of CNS cancer.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive transcranial direct current stimulation (tDCS) with concurrent cognitive training
Follow-up
Participants are monitored for safety and effectiveness after treatment
What Are the Treatments Tested in This Trial?
Interventions
- Questionnaires
- tDCS
Find a Clinic Near You
Who Is Running the Clinical Trial?
Memorial Sloan Kettering Cancer Center
Lead Sponsor