Non-fluoride Whitening Toothpaste for Tooth Discoloration
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial tests a non-fluoride whitening toothpaste to compare its stain-removal effectiveness against a regular fluoride toothpaste. The goal is to determine if the whitening toothpaste brightens smiles more effectively over an 8-week period. It suits individuals who brush daily, drink tea or coffee regularly, and wish to try a new whitening option. Participants must avoid other whitening products during the trial. As an unphased trial, this study provides a unique opportunity to explore new dental care options without the constraints of traditional clinical trial phases.
Do I need to stop taking my current medications for the trial?
Yes, if your current medications might affect oral tissue condition, salivation, or stain formation, you may need to stop taking them to participate in the trial.
Is there any evidence suggesting that this trial's treatments are likely to be safe?
Research has shown limited information about the safety of over-the-counter whitening products. Some studies have found these products more effective at whitening than regular toothpaste. However, information on their long-term safety remains scarce.
Users of these toothpastes might experience side effects such as sensitive teeth or irritated gums. The non-fluoride whitening toothpaste being tested has not been associated with serious problems, but individual reactions can vary.
Since this trial is not in its early stages, specific safety data for this product is limited. However, due to its similarity to other over-the-counter products, it is likely safe for most people. Consulting a dentist before trying new whitening treatments is advisable, especially if there are concerns about side effects.12345Why are researchers excited about this trial?
Researchers are excited about the non-fluoride whitening toothpaste because it offers a new approach to tackling tooth discoloration. Unlike standard whitening toothpastes, which typically rely on fluoride and abrasive agents to remove stains, this innovative toothpaste may use alternative ingredients to achieve whitening without fluoride, potentially making it a safer choice for those sensitive to fluoride or looking for a gentler option. This opens the door for broader use, including for individuals who prefer natural or non-fluoride dental care products, while still targeting and reducing tooth discoloration effectively.
What evidence suggests that this non-fluoride whitening toothpaste could be effective for tooth discoloration?
Research has shown that whitening toothpastes effectively remove surface stains from teeth. In this trial, participants will use either a non-fluoride whitening toothpaste or a non-whitening fluoride toothpaste. Studies have found that whitening products, including those without fluoride, often outperform regular toothpastes in removing discoloration. For instance, research found that whitening toothpastes consistently improved tooth color. However, some reviews suggest that their ability to deeply bleach teeth might be limited. In summary, non-fluoride whitening toothpastes can make teeth look whiter by removing stains, but their deep bleaching power remains uncertain.13456
Who Is on the Research Team?
Jeffery L Milleman, DDS, MPA
Principal Investigator
Salus Research, Inc.
Are You a Good Fit for This Trial?
This trial is for individuals with tooth discoloration who are interested in testing the effectiveness of a non-fluoride whitening toothpaste compared to a non-whitening fluoride toothpaste over 8 weeks. The specific eligibility criteria have not been provided.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants use either a non-fluoride whitening toothpaste or a non-whitening fluoride toothpaste for 8 weeks
Follow-up
Participants are monitored for safety and effectiveness after treatment
What Are the Treatments Tested in This Trial?
Interventions
- Non-fluoride Whitening Toothpaste
- Non-whitening Fluoride Toothpaste
Find a Clinic Near You
Who Is Running the Clinical Trial?
Boka LLC
Lead Sponsor