Spinal Cord + Electrical Stimulation for Muscle Activity
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial aims to explore how different types of electrical stimulation can activate muscles in people without disabilities. Researchers are testing two methods: a non-invasive technique called transcutaneous spinal cord stimulation (tSCS) and another called functional electrical stimulation (FES), to assess their effects on muscle activity at the ankle. They will also test the combination of both methods to determine if it leads to better results. Healthy individuals who can walk unaided and are comfortable with the stimulation methods may be suitable for this study. As an unphased trial, this study offers participants the opportunity to contribute to innovative research in muscle activation techniques.
Will I have to stop taking my current medications?
The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your doctor.
What prior data suggests that this protocol is safe for muscle activity in spinal cord injury patients?
Research has shown that Functional Electrical Stimulation (FES) is safe for individuals with spinal cord injuries. Studies have found that FES can safely activate muscles, even for those with walking difficulties. People with multiple sclerosis have also used FES safely to exercise their muscles.
For Transcutaneous Spinal Cord Stimulation (tSCS), several studies suggest it is a safe, non-invasive method to assist with muscle activity. Safety checks during these studies revealed no major problems, and participants generally tolerated the treatment well. This method has been explored as a safe option for aiding recovery from spinal cord injuries.
Both treatments have been tested in various settings and found to be safe. Participants in these studies did not report any serious side effects, making these promising options for those considering joining a trial.12345Why are researchers excited about this trial?
Researchers are excited about Functional Electrical Stimulation (FES) and Transcutaneous Spinal Cord Stimulation because these techniques offer a non-invasive way to activate muscle activity. Unlike current treatments that may rely on invasive surgical procedures or medications that can have significant side effects, these methods use electrical currents applied externally to stimulate the spinal cord and muscles. This new approach could potentially enhance muscle function without the risks associated with surgery or pharmaceuticals, offering a safer and possibly more effective option for improving muscle activity.
What evidence suggests that combining tSCS and FES could be effective for muscle activation in spinal cord injury?
Research has shown that Functional Electrical Stimulation (FES), a treatment in this trial, can strengthen muscles weakened by spinal cord injuries. Studies indicate that FES can increase muscle size and strength, especially in muscles used for walking. This suggests that FES might help people regain some muscle control and movement.
Transcutaneous Spinal Cord Stimulation (tSCS), another treatment option in this trial, also shows promise. Research has found that it can improve movement in the arms and legs, aiding those with spinal cord injuries. When combined with activity-based training, tSCS has enhanced muscle strength and walking ability.
Evidence suggests that using FES and tSCS together, as explored in this trial, might activate muscles more effectively than using either one alone. This combination could significantly improve movement and muscle function for individuals with spinal cord injuries.678910Are You a Good Fit for This Trial?
This trial is for individuals with spinal cord injury who may have weakened or paralyzed muscles. It's designed to test if non-invasive treatments can help activate these muscles. Participants should be able to undergo ultrasound and electrical stimulation safely.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants undergo transcutaneous spinal cord stimulation (tSCS) and functional electrical stimulation (FES) to quantify ankle joint torque and muscle activation
Follow-up
Participants are monitored for safety and effectiveness after treatment
What Are the Treatments Tested in This Trial?
Interventions
- Functional Electrical Stimulation
- Transcutaneous (Non-Invasive) Spinal Cord Stimulation
- Ultrasound
Find a Clinic Near You
Who Is Running the Clinical Trial?
North Carolina State University
Lead Sponsor
University of North Carolina, Chapel Hill
Collaborator