Heat Therapy for Prediabetes

(HEAT Trial)

This trial tests whether using heat pads on the legs improves muscle health and blood sugar control as effectively as high-intensity interval training (HIIT) in older individuals with prediabetes. By comparing heat therapy to exercise, researchers aim to determine if heat can mimic or enhance the benefits of exercise. Suitable candidates for this trial are individuals over 50 with prediabetes who lead a mostly inactive lifestyle and are not on certain medications. As an unphased trial, participants can contribute to innovative research that may provide new, non-exercise options for managing prediabetes.

Yes, you will need to stop taking certain medications that could interfere with the study, such as corticosteroids, opiates, benzodiazepines, tricyclic antidepressants, beta blockers, sulfonylureas, insulin, metformin, anticoagulants, barbiturates, insulin sensitizers, and fibrates.

Research has shown that heat therapy is generally safe for most people, including those with type 2 diabetes. One study found that participants using heat therapy experienced better blood sugar control without major side effects. Another study observed changes in blood pressure, but these were not harmful.

For high-intensity interval training (HIIT), studies have demonstrated its safety for most people, including those with prediabetes. HIIT can enhance heart health and blood sugar levels. It can be tailored to each person’s fitness level, reducing the risk of injury.

Researchers are excited about using heat therapy for prediabetes because it offers a non-invasive way to potentially improve blood sugar regulation. Traditional treatments for prediabetes often include lifestyle changes and medications to enhance insulin sensitivity. However, heat therapy works by raising the muscle temperature, which may mimic some of the beneficial effects of exercise without the physical exertion. High-intensity interval training, another part of the study, is already known for its efficiency in boosting cardiovascular health and improving insulin sensitivity. By comparing heat therapy's effects with other methods, researchers hope to uncover new, accessible ways to manage or even prevent the progression of prediabetes.

Research has shown that heat therapy, one of the treatments in this trial, might help manage blood sugar levels, particularly in older adults at risk for metabolic issues. Some studies have found benefits for people with type 2 diabetes, but further research is needed to confirm these findings.