Atlas Knee System for Osteoarthritis

(Atlas-USA Trial)

The trial aims to test the safety and effectiveness of the Atlas Knee System for individuals with medial knee osteoarthritis, a type of arthritis affecting the inner knee. The focus is on evaluating how well this device reduces pain and improves knee function over two years post-surgery. This trial may suit those experiencing knee pain primarily on the inside, worsened by activities like walking, and who have not found relief from treatments such as physical therapy or pain medication. As an unphased trial, it offers a unique opportunity to contribute to medical research and potentially benefit from an innovative treatment.

The trial protocol does not specify whether you need to stop taking your current medications. However, if you are on medications that affect bone metabolism or systemic steroids, you may need to discuss this with the trial team.

Research has shown that the Atlas Knee System is generally well-tolerated by patients with medial knee osteoarthritis. One study found the device to be safe over three years, with 97.3% of the implants functioning well without needing removal or replacement. Another study reported that 96.2% of patients experienced significant pain relief, indicating that the device not only reduces pain but is also safe for most users. Patients noted improvements in daily activities and overall knee function.

The Atlas Knee System is unique because it directly targets medial knee osteoarthritis using a specialized device, rather than standard treatments like pain medication or physical therapy. Unlike surgical options such as total knee replacement, the Atlas Knee System offers a less invasive alternative, potentially reducing recovery time and surgical risks. Researchers are excited about this treatment because it may provide effective relief by mechanically supporting the knee joint, offering a novel approach that could improve mobility and quality of life for patients with knee osteoarthritis.

Studies have shown that the Atlas Knee System, which participants in this trial will receive, can significantly aid individuals with medial knee osteoarthritis, a type of arthritis affecting the inner knee. Research indicates that about 96% of patients experienced at least a 20% reduction in pain after 12 months. Another study found that the device's benefits, which help reduce stress on the knee joint, last for at least two years. Additionally, the device maintains a high three-year survival rate of 97.3%, meaning it remains effective and intact over time. This evidence suggests the Atlas Knee System could be a promising option for managing knee pain and improving knee function.¹²³⁴⁵