mHealth Strategies for Cancer Survivors

(AYAWell Trial)

This trial aims to help young cancer survivors manage their weight using mobile health (mHealth) tools. It compares a guided program, the AYA WELL Intervention, which includes personalized nutrition and exercise goals, to a self-guided approach with digital tools and peer support. The trial seeks participants aged 18-39 who were diagnosed with cancer as teenagers or young adults, have completed treatment at least six months ago, and are currently dealing with overweight or obesity. As an unphased trial, this study offers participants a unique opportunity to contribute to innovative research that could enhance weight management strategies for young cancer survivors.

The trial does not specify if you need to stop taking your current medications, but you cannot participate if you are using certain medications that affect appetite or weight, unless you are on a stable dose of SSRIs (a type of antidepressant) for 3 months.

Research shows that digital health programs, such as the AYA WELL program, are generally safe for young cancer survivors. Studies with similar digital tools have found that participants handle them well. For instance, a study with a positive psychology chatbot for young cancer survivors showed good participation and no serious safety issues. Although specific safety data for the AYA WELL program is not yet available, other studies using digital tools and personalized health advice have not reported major problems. This suggests the program is likely safe for participants.¹²³⁴⁵

Researchers are excited about the mHealth strategies being tested for cancer survivors because they offer a personalized and interactive approach to recovery. Unlike standard care options that might include general advice on diet and exercise, this intervention utilizes a mobile web app to provide tailored goals for nutrition and physical activity, enriched with psychoeducation and behavioral skills training. The inclusion of digital tools like a smart scale and activity tracker, combined with a moderated social networking group, fosters a supportive community and encourages daily engagement. This comprehensive, tech-driven approach aims to enhance self-monitoring and long-term well-being in a way that traditional treatments do not.

Research shows that mobile health (mHealth) tools can help young cancer survivors manage their weight. Studies have found that these digital tools can improve exercise and eating habits in this group. In this trial, participants in the intervention arm will receive the AYA WELL Intervention, which offers personalized nutrition and exercise goals, training in healthy habits, and peer support through a mobile app. Users of similar digital methods have reported positive changes in their health behaviors. This evidence suggests that the AYA WELL Intervention could effectively help cancer survivors manage their weight.¹⁶⁷⁸⁹