Acoustic Resonance Therapy for Empty Nose Syndrome

This trial explores whether Acoustic Resonance Therapy (ART), which uses sound vibrations, can alleviate symptoms of Empty Nose Syndrome (ENS). ENS often feels like nasal congestion, even when the nose is clear, and ART aims to improve this by using sound to open the nasal passages. Participants will receive either personalized ART or a standard version to determine which is more effective. Individuals diagnosed with ENS who have undergone turbinate reduction surgery may be suitable candidates. As an unphased trial, this study provides a unique opportunity to explore innovative treatment options for ENS.

The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your doctor.

Research has shown that Acoustic Resonance Therapy (ART) is safe. The FDA has approved ART for treating common nasal blockages, indicating it has passed safety tests for other uses. In one study using ART, participants reported no adverse side effects and experienced significant relief from nasal congestion, suggesting ART is gentle on the body. It works by using sound vibrations to clear nasal blockages and improve breathing. For those considering joining this trial, the safety information appears promising.¹²³⁴⁵

Researchers are excited about Acoustic Resonance Therapy (ART) for Empty Nose Syndrome because it offers a novel approach compared to current treatments like nasal saline irrigations and surgical interventions. Unlike these traditional methods, ART uses sound waves to potentially restore nasal function and sensation. The personalized ART approach tailors the therapy to individual needs, which might enhance effectiveness. This innovative technique provides a non-invasive alternative that could improve quality of life for those affected by this challenging condition.

Studies have shown that Acoustic Resonance Therapy (ART) can effectively treat nasal congestion. In a small initial study, ART helped with sudden nasal congestion by using sound vibrations to improve airflow. ART sends specific sound frequencies to the nasal passages, breaking up mucus and reducing swelling. For conditions like allergic rhinitis (a type of nasal allergy) and chronic rhinosinusitis (long-term sinus inflammation), ART may increase nitric oxide production, improve mucus movement, and alter immune responses. Although the FDA has approved ART for regular nasal blockage, its potential to treat Empty Nose Syndrome (ENS) remains under investigation. This trial will compare Personalized ART and Non-personalized ART to evaluate their effectiveness in treating ENS.¹²⁶⁷⁸