44 Participants Needed

Lung Cancer Screening Education for Head and Neck Cancer Survivors

(GUIAR Trial)

CO
Overseen ByCoral Olazagasti
Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: University of Miami
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial aims to help Hispanic/LatinX survivors of head and neck cancer determine their eligibility for lung cancer screening and identify any barriers they might face. Participants will receive either intensive education about lung cancer screening and tobacco cessation or standard screening care. The trial seeks survivors treated for head and neck cancer at least five years ago, with a history of heavy smoking, who qualify for lung cancer screening. This trial may suit individuals fitting this profile who wish to learn more about lung cancer risks and prevention. As an unphased trial, it offers participants a unique opportunity to contribute to research that could enhance lung cancer screening processes and outcomes for others.

Will I have to stop taking my current medications?

The trial information does not specify whether you need to stop taking your current medications. It is best to discuss this with the trial coordinators or your doctor.

What prior data suggests that this lung cancer screening education is safe for head and neck cancer survivors?

Research shows that lung cancer screening with low-dose CT scans is generally safe and manageable for most people. This method can detect lung cancer earlier and reduce the risk of death. However, it may lead to false alarms, resulting in unnecessary and potentially uncomfortable tests.

Studies on educational programs about lung cancer screening have shown positive outcomes. These programs assist doctors and nurses in determining who should be screened and increase screening rates. No safety issues have been reported with these educational programs, making them a safe option for those considering participation.12345

Why are researchers excited about this trial?

Researchers are excited about this trial because it explores a new approach to lung cancer screening for head and neck cancer survivors. Unlike standard care, which typically involves routine imaging and check-ups, this trial offers intensive lung cancer screening education combined with tobacco cessation support. This unique approach aims to better educate patients about the benefits of early screening and quitting smoking, potentially leading to earlier detection of lung cancer and improved health outcomes. By focusing on education and behavior change, researchers hope to empower patients, reduce cancer risk, and improve survival rates.

What evidence suggests that this trial's treatments could be effective for lung cancer screening in head and neck cancer survivors?

Research has shown that low-dose CT scans can detect lung cancer early in high-risk individuals, such as those with a history of head and neck cancer. In this trial, participants in the Lung Cancer Screening Education Group will receive intensive lung cancer screening and tobacco cessation education. One study found that healthcare providers who received special training in lung cancer screening identified more patients who needed screening, leading to increased screening rates. Early detection through these screenings has proven to reduce the death rate from lung cancer, making it a crucial option for those at high risk.14678

Who Is on the Research Team?

CO

Coral Olazagasti

Principal Investigator

University of Miami

Are You a Good Fit for This Trial?

This trial is for Hispanic/LatinX adults over 18 who are head and neck cancer survivors, treated at least 5 years ago without recurrence. They must meet lung cancer screening criteria: either a history of heavy smoking or fitting the age/smoking profile per USPSTF21/NCCN guidelines. Pregnant/nursing individuals, those with recent lung imaging, active cancers, or less than a 20 pack-year smoking history cannot join.

Inclusion Criteria

I survived head and neck cancer, treated over 5 years ago with no recurrence.
You must consider yourself to be Hispanic/LatinX.
You need to be able to understand and sign a form that explains the study.
See 1 more

Exclusion Criteria

I have had head and neck cancer that spread to distant parts of my body.
I have not had head or neck treatment in the last 5 years.
I have smoked less than 20 pack-years.
See 4 more

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Education and Survey

Participants receive intensive lung cancer screening and tobacco cessation education and complete survey questionnaires to assess awareness and perception of lung cancer screening recommendations

Up to 2 years

Follow-up

Participants are monitored for changes in awareness and perception of lung cancer screening recommendations and undergo early detection lung cancer screening

Up to 2 years

What Are the Treatments Tested in This Trial?

Interventions

  • Lung Cancer Screening Education
  • Semi-Structured Interview
  • Standard of Care Lung Cancer Screening Program
Trial Overview The study aims to evaluate awareness about lung cancer screening in Hispanic/LatinX head and neck cancer survivors through surveys and interviews. It will also explore barriers to screening participation and provide education on the importance of regular screenings.
How Is the Trial Designed?
2Treatment groups
Experimental Treatment
Group I: Standard of Care Control GroupExperimental Treatment1 Intervention
Group II: Lung Cancer Screening Education GroupExperimental Treatment3 Interventions

Find a Clinic Near You

Who Is Running the Clinical Trial?

University of Miami

Lead Sponsor

Trials
976
Recruited
423,000+

LUNGevity Foundation

Collaborator

Trials
8
Recruited
1,600+

National Cancer Institute (NCI)

Collaborator

Trials
14,080
Recruited
41,180,000+

Published Research Related to This Trial

Lung cancer screening using low-dose CT (LDCT) has proven effective in clinical trials, including the National Lung Screening Trial, highlighting its importance in early detection.
The Lung CT Screening Reporting and Data System (Lung-RADS) is recommended for all LDCT exams to improve communication of results and reduce false-positive rates, ensuring better patient care.
Screening for Lung Cancer: Lexicon for Communicating With Health Care Providers.Carter, BW., Lichtenberger, JP., Wu, CC., et al.[2018]
In a study of 121 patients who underwent low-dose computed tomography (LDCT) screening for lung cancer, the overall adherence rate to follow-up scans was only 59.1%, indicating a need for improved compliance with screening guidelines.
Patients with more concerning findings (Lung-RADS score 2) were 2.43 times more likely to adhere to follow-up scans compared to those with less concerning findings (Lung-RADS score 1), while African American patients showed lower odds of adherence, highlighting potential socioeconomic disparities in lung cancer screening compliance.
Patient Adherence in an Academic Medical Center's Low-dose Computed Tomography Screening Program.Mortman, KD., Devlin, J., Giang, B., et al.[2023]
Clinicians acknowledge that low-dose computed tomography (LDCT) lung cancer screening (LCS) can be beneficial for some survivors of head and neck cancer (HNC) with a history of smoking, but they face significant challenges in implementing shared decision-making (SDM) practices.
Barriers to effective LCS implementation include time constraints, unclear guidelines, lack of tailored decision aids, and competing patient priorities, indicating a need for further research and refinement of current screening guidelines.
Attitudes of Clinicians about Screening Head and Neck Cancer Survivors for Lung Cancer Using Low-Dose Computed Tomography.Dukes, K., Seaman, AT., Hoffman, RM., et al.[2022]

Citations

Lung Cancer Screening with Low-Dose Computed ...This review provides an update on lung cancer screening with low-dose computed tomography (LDCT) and its implications for primary care providers.
Incidence of Second Primary Lung Cancer After Low-Dose ...Objective To evaluate the incidence of second primary lung cancer in survivors of head and neck cancer survivors with screening low-dose ...
Lung Cancer Screening in Head and Neck CancerLung cancer screening is as an effective strategy for early diagnosis in high-risk patients, with proven impact on decreasing mortality.
A Lung Cancer Screening Education Program Impacts both ...Conclusions: A targeted LCS educational program improves provider and MAs' ability to identify eligible LCS patients and is associated with an increase in the ...
Lung Cancer Screening in Cancer Survivors vs Those ...This cohort study compares characteristics, low-dose computed tomography interpretation, lung cancer detection rates, and all-cause ...
Screening for Lung Cancer With Low-Dose Computed ...Screening high-risk persons with LDCT can reduce lung cancer mortality but also causes false-positive results leading to unnecessary tests and invasive ...
Lung Cancer ScreeningScreening with low-dose computed tomography (CT) scan has resulted in earlier detection and has led to a decrease in lung cancer mortality.
A Lung Cancer Screening Education Program Impacts both ...A targeted LCS educational program improves provider and MAs' ability to identify eligible LCS patients and is associated with an increase in the number of ...
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