Consultation + Digital Outreach for Colorectal Cancer Screening

(YVONNE-DX Trial)

AA
JN
Overseen ByJordan Neil, PhD
Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: University of Oklahoma
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial aims to improve colorectal cancer care among Native Americans by increasing the follow-up rate for colonoscopies after an abnormal home stool test. Participants will receive either in-person consultations or digital outreach, including SMS texts with culturally relevant content and telehealth consultations for convenience. The trial seeks Native American participants who live in Oklahoma and have access to email. As an unphased trial, this study offers a unique opportunity to contribute to culturally tailored healthcare improvements.

Will I have to stop taking my current medications?

The trial information does not specify whether you need to stop taking your current medications.

Is there any evidence suggesting that this trial's treatments are likely to be safe?

Research shows that digital methods, such as text messages and videos, effectively and safely encourage colorectal cancer screening. Previous studies found no major safety issues with these methods. Personalized digital outreach increased screening rates by about 20.9%, demonstrating their effectiveness and safety.

Studies also find telehealth consultations safe and well-received. They help patients avoid long trips, making medical care more accessible without added risks.

Overall, both digital outreach and telehealth consultations are safe, with no major problems reported in past research.12345

Why are researchers excited about this trial?

Researchers are excited about this trial because it explores innovative ways to improve colorectal cancer screening among Cheyenne and Arapaho Tribal members. Unlike traditional methods, which often involve multiple in-person appointments, this trial tests a digital outreach approach using SMS texts and videos tailored to cultural sensitivities, aiming to motivate patients to schedule a colonoscopy. Additionally, it proposes a telehealth consultation for the pre-procedure appointment, potentially overcoming significant transportation barriers due to the long distance to the clinic. This approach not only seeks to increase screening rates but also enhances accessibility and convenience for patients who live far from medical facilities.

What evidence suggests that this trial's treatments could be effective for colorectal cancer screening?

This trial will compare two approaches to increase colorectal cancer screening: In-Person Consultation and mHealth Outreach with Telehealth Consultation. Research has shown that digital methods can effectively increase the number of people getting screened for colorectal cancer. For example, one study found that personalized phone calls led to a 21% increase in screenings. Digital tools like text messages and videos can remind and encourage people to get screened. Another study discovered that digital guidance helped more people complete stool DNA tests for screening. Overall, digital approaches often outperform traditional methods in motivating people to get screened for colorectal cancer.12456

Who Is on the Research Team?

JN

Jordan Neil, PhD

Principal Investigator

University of Oklahoma

Are You a Good Fit for This Trial?

This trial is for Native Americans who have had an abnormal home stool screening indicating a potential risk for colorectal cancer. It aims to improve follow-up diagnostic colonoscopy rates in this group to enhance health equity and reduce CRC disparities.

Inclusion Criteria

I have access to email.
I am between 45 and 75 years old.
Live in Oklahoma
See 2 more

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Stage 1: Co-development

Co-develop culturally sensitive digital outreach intervention strategies through focus groups and community advisory board discussions

6 months
Focus groups and advisory board meetings

Stage 2: Intervention Testing

Test the reach, feasibility, and potential efficacy of digital outreach intervention strategies using a 2 x 2 factorial design

6 months
Telehealth and in-person consultations

Follow-up

Participants are monitored for the effectiveness of the intervention strategies in increasing diagnostic colonoscopy rates

60 days post-randomization

What Are the Treatments Tested in This Trial?

Interventions

  • Digital Outreach
  • In Person consultation
Trial Overview The study tests whether in-person consultations or digital outreach methods are more effective at increasing the rate of timely diagnostic colonoscopies following abnormal home stool screenings among Native Americans.
How Is the Trial Designed?
2Treatment groups
Experimental Treatment
Active Control
Group I: mHealth Outreach and Telehealth ConsultationExperimental Treatment1 Intervention
Group II: In Person ConsultationActive Control1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

University of Oklahoma

Lead Sponsor

Trials
484
Recruited
95,900+

Citations

Digital health interventions for colorectal cancer screening ...Outcomes from digital interventions were mostly positive. For example, tailored telephone outreach increased screening rates by 20.9% (Basch, ...
Impact of Digital Navigation on Screening Adherence With ...This study evaluated the impact of different digital outreach channels on patient adherence to CRC screening with a multi-target stool DNA (mt-sDNA) test in a ...
Qualitative Outcomes of Colorectal Cancer Screening ...Background/Objectives: Despite its effectiveness, colorectal cancer (CRC) screening rates are suboptimal in the United States.
How effective are digital technology-based interventions at ...This meta-analysis seeks to examine the usefulness of digital interventions in promoting CRC screening uptake as compared to existing non-digital strategies.
Population Health Colorectal Cancer Screening Strategies ...This trial evaluates the most effective population health strategy to promote colorectal cancer screening among average-risk adults aged 45 ...
Consultation + Digital Outreach for Colorectal Cancer ...This trial is for Native Americans who have had an abnormal home stool screening indicating a potential risk for colorectal cancer. It aims to improve follow-up ...
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