Breathing Muscle Training for Childhood Cancer Survivors
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial aims to determine if a breathing exercise program can help childhood cancer survivors improve their breathing during exercise. Participants will use the POWERbreathe Plus device, a breathing muscle training tool, to train their breathing muscles at home for six weeks. The trial seeks survivors who completed cancer treatment over a year ago and do not have serious breathing or movement limitations. The goal is to make exercise easier and more comfortable by strengthening the muscles used for breathing. As an unphased trial, this study offers participants the chance to contribute to valuable research that could enhance the quality of life for childhood cancer survivors.
Do I need to stop my current medications for this trial?
The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your doctor.
What prior data suggests that this breathing muscle training is safe for childhood cancer survivors?
Research shows that inspiratory muscle training (IMT), such as the POWERbreathe Plus device used in this trial, is generally safe. Studies have found that IMT involves no drugs and does not cause side effects or interfere with medications, making it a low-risk method to enhance breathing strength. Previous studies with hospital patients using similar devices for several weeks reported no major safety issues. With over 20 years of research supporting it, the POWERbreathe Plus has proven effective in reducing breathlessness without causing harm. This evidence suggests that the treatment is well-tolerated and safe for participants.12345
Why are researchers excited about this trial?
Unlike traditional treatments for childhood cancer survivors that often focus on medication and physical therapy, the POWERbreathe Plus IMT is a unique approach because it involves inspiratory muscle training, a specific type of breathing exercise. This device targets the strengthening of breathing muscles, potentially improving respiratory function more directly and efficiently than conventional methods. Researchers are excited about this non-invasive, home-based technique because it empowers patients to actively participate in their recovery, offering a personalized and convenient option that could enhance quality of life without the side effects associated with medications.
What evidence suggests that this inspiratory muscle training is effective for childhood cancer survivors?
Research shows that inspiratory muscle training (IMT), such as using the POWERbreathe Plus device, can help cancer survivors enhance lung function and physical fitness. One study found that using a device similar to the POWERbreathe Plus increased breathing muscle strength by 54% in just four weeks, significantly strengthening the muscles used for breathing. Although specific information about IMT for childhood cancer survivors is limited, these findings offer hope for improving breathing during exercise. Experts generally agree that strengthening these muscles can enhance overall fitness and quality of life. Participants in this trial will use the POWERbreathe Plus device for inspiratory muscle training to assess its effectiveness in childhood cancer survivors.16789
Who Is on the Research Team?
Simon Ho
Principal Investigator
University of Maryland, Baltimore
Are You a Good Fit for This Trial?
This trial is for childhood cancer survivors who finished treatment (like chemo, surgery, or radiation) at least a year ago. It's not for those who had central nervous system cancers. Participants should be interested in improving their breathing muscles through training.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Baseline Assessment
Participants undergo pulmonary function and muscle performance tests followed by treadmill walking trials with expired gas analysis
Treatment
Participants perform inspiratory muscle training at home for 6 weeks with weekly telehealth follow-ups
Follow-up
Participants return for a follow-up visit to undergo the same assessments as the baseline visit
What Are the Treatments Tested in This Trial?
Interventions
- POWERbreathe Plus IMT
POWERbreathe Plus IMT is already approved in European Union, United States, Canada for the following indications:
- Asthma
- COPD
- Bronchitis
- Cystic Fibrosis
- Heart Failure
- Spinal Injury
- Respiratory Conditions
- Asthma
- COPD
- Bronchitis
- Cystic Fibrosis
- Heart Failure
- Spinal Injury
- Respiratory Conditions
- Asthma
- COPD
- Bronchitis
- Cystic Fibrosis
- Heart Failure
- Spinal Injury
- Respiratory Conditions
Find a Clinic Near You
Who Is Running the Clinical Trial?
University of Maryland, Baltimore
Lead Sponsor