Acupuncture for Hot Flashes in Breast Cancer
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial explores whether acupuncture can reduce hot flashes in individuals with a history of breast cancer. Acupuncture involves inserting thin needles into specific body points to aid natural healing. Two groups will be tested: one receives immediate acupuncture twice a week for 10 weeks, while the other starts with usual care and switches to weekly acupuncture after 10 weeks. The trial seeks participants with breast cancer who experience frequent hot flashes, at least two per day, while on hormonal therapy. As an unphased trial, it offers participants the opportunity to explore a non-drug treatment option for managing hot flashes.
Will I have to stop taking my current medications?
You can continue taking your current medications for hot flashes if you've been on them for more than 4 weeks and keep the dose the same during the study. If you recently started a new medication for hot flashes, you might need to wait until you've been on it for at least 4 weeks before joining the study.
What prior data suggests that acupuncture is safe for reducing hot flashes in breast cancer patients?
Research has shown that acupuncture is generally safe for treating symptoms like hot flashes. In past studies involving over 150 women, acupuncture proved to be a safe method for managing menopause-related symptoms. A 2018 review of 12 studies found acupuncture more effective than no treatment for certain types of pain, supporting its safety. These studies reported no serious side effects, suggesting that acupuncture is well-tolerated.12345
Why are researchers excited about this trial?
Researchers are excited about using acupuncture for managing hot flashes in breast cancer patients because it offers a unique, drug-free alternative to traditional hormone therapies like estrogen replacement or medications such as gabapentin and clonidine. Acupuncture works by inserting thin needles into specific points on the body, which may help regulate body temperature and reduce the frequency and severity of hot flashes. This approach is particularly appealing for breast cancer patients who often seek non-hormonal options to avoid potential interactions or side effects with their ongoing cancer treatments. By providing a holistic and non-invasive method, acupuncture could offer a natural way to manage symptoms, enhancing the quality of life for these patients.
What evidence suggests that acupuncture might be an effective treatment for hot flashes?
Research has shown that acupuncture might help reduce hot flashes in people with breast cancer. Some studies have found that acupuncture can significantly improve hot flashes and related symptoms. In this trial, participants will be divided into two groups: one will receive immediate acupuncture treatments, while the other will initially receive standard care without acupuncture, followed by delayed acupuncture treatments. Patients in these studies reported fewer hot flashes and improved quality of life after acupuncture treatments. Acupuncture may also help with other symptoms like tiredness and pain from breast cancer treatments. While more research is needed to confirm these benefits, current evidence is promising.678910
Who Is on the Research Team?
Weidong Lu, PhD, MPH
Principal Investigator
Dana-Farber Cancer Institute
Are You a Good Fit for This Trial?
This trial is for adults over 18 with Stage I-III hormone receptor-positive breast cancer who've finished primary treatment and are on hormonal therapy. They must have frequent hot flashes, be in good physical condition, and not planning further chemotherapy or surgery during the study.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Immediate Acupuncture group receives acupuncture twice a week for 10 weeks; Delayed Acupuncture group receives usual care for 10 weeks
Crossover Treatment
Delayed Acupuncture group receives acupuncture once a week for 10 weeks; Immediate Acupuncture group receives usual care for 10 weeks
Follow-up
Participants are monitored for safety and effectiveness after treatment
What Are the Treatments Tested in This Trial?
Interventions
- Acupuncture
Acupuncture is already approved in United States, European Union, China for the following indications:
- Pain management
- Hot flashes
- Fatigue
- Sleep disturbances
- Anxiety
- Depression
- Neuropathy
- Pain management
- Hot flashes
- Fatigue
- Sleep disturbances
- Anxiety
- Depression
- Pain management
- Hot flashes
- Fatigue
- Sleep disturbances
- Anxiety
- Depression
- Neuropathy
Find a Clinic Near You
Who Is Running the Clinical Trial?
Dana-Farber Cancer Institute
Lead Sponsor
The Comprehensive and Integrative Medicine Institute of South Korea
Collaborator