Genetic Testing for Breast Cancer
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial aims to explore how a new genetic counseling method might influence surgical decisions for individuals recently diagnosed with breast cancer. Participants will undergo genetic testing and receive guidance through either standard genetic counseling or a new approach using tables and graphs, known as quantitative genetic counseling. The study targets those who are newly diagnosed, proficient in English, and prepared to make surgical decisions. Eligible participants should not have had breast cancer previously and must be cleared for surgery. As an unphased trial, this study offers participants the chance to contribute to innovative research that could enhance decision-making tools for future patients.
Will I have to stop taking my current medications?
The trial information does not specify whether you need to stop taking your current medications.
What prior data suggests that these genetic counseling methods are safe?
Research has shown that genetic counseling, whether conducted traditionally or with charts and graphs, is generally safe and well-received by patients. In past studies, participants reported high satisfaction with genetic counseling. For instance, one study found that 94.9% of participants felt their questions about hereditary breast cancer were answered after counseling and testing. This suggests that the process is not only informative but also easy for patients to navigate.
These trials focus on counseling methods, which involve discussion and education, not medical procedures. Therefore, patients need not worry about physical side effects. The counseling helps patients understand their genetic test results, guiding important health decisions. Based on available data, these methods appear safe and well-tolerated.12345Why are researchers excited about this trial?
Researchers are excited about this trial because it explores different approaches to genetic counseling for breast cancer, which could revolutionize patient understanding and decision-making. Unlike standard genetic counseling, which involves a typical discussion format, quantitative genetic counseling uses tables and graphs to guide the conversation. This visual approach could make complex genetic information more accessible and easier to understand for patients, potentially leading to more informed choices about their health. By comparing these two methods, researchers hope to identify a counseling technique that enhances patient comprehension and satisfaction.
What evidence suggests that these genetic counseling methods are effective for breast cancer?
This trial will compare two methods of genetic counseling for breast cancer patients: Standard Genetic Counseling and Quantitative Genetic Counseling. Research has shown that genetic counseling aids breast cancer patients in making treatment decisions. Studies have found that using charts and graphs during genetic counseling, as in the Quantitative Genetic Counseling arm of this trial, helps patients better understand their test results. This understanding can lead to more informed choices about surgery. Specifically, one study found that this method can speed up receiving test results by up to 85%, which is crucial for timely decision-making. Overall, patients report high satisfaction with genetic counseling, indicating it is a valuable part of managing their treatment.13678
Who Is on the Research Team?
Tara King, MD
Principal Investigator
Dana-Farber Cancer Institute
Are You a Good Fit for This Trial?
This trial is for English-speaking adults aged 18-78 with a new breast cancer diagnosis who are cleared for surgery and considering genetic testing. It's not for those with metastatic or bilateral breast cancer, previous breast cancers, certain other malignancies, or prior broad-based panel genetic testing.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Genetic Counseling
Participants receive genetic testing and are placed into either standard or quantitative genetic counseling groups
Follow-up
Participants are monitored for changes in risk assessment, anxiety levels, and satisfaction with genetic counseling
Optional Extension
Participants may opt into an extension of the study for further monitoring and counseling
What Are the Treatments Tested in This Trial?
Interventions
- Quantitative Genetic Counseling
- Standard Genetic Counseling
Find a Clinic Near You
Who Is Running the Clinical Trial?
Dana-Farber Cancer Institute
Lead Sponsor
Myriad Genetics, Inc.
Industry Sponsor