Citicoline Supplement for Alzheimer's Disease

This trial explores whether a citicoline supplement can improve sleep and thinking skills in people with Alzheimer's disease. Previous studies suggest citicoline might help with memory issues. This trial aims to determine if it can also address sleep problems, which affect many with Alzheimer's and their caregivers. Participants will receive either the citicoline supplement or a placebo (a substance with no active ingredients). Ideal candidates for this trial are those diagnosed with Alzheimer's disease, living in the continental U.S., and experiencing sleep disturbances.

As an unphased trial, participants can contribute to groundbreaking research that could enhance the quality of life for those with Alzheimer's.

The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your doctor.

Research has shown that citicoline, a dietary supplement, is safe and well-tolerated. Studies found that people with Alzheimer's disease who took citicoline experienced no serious side effects. Citicoline has been safely used in various groups of people with Alzheimer's at the same dose as in this trial. It is also known for effectively reaching the brain. Overall, evidence suggests that citicoline is safe for people, particularly those with Alzheimer's disease.¹²³⁴⁵

Unlike the standard treatments for Alzheimer's disease, which often focus on managing symptoms with medications like Donepezil or Memantine, the citicoline supplement is unique because it targets the brain's cellular health. Citicoline is a naturally occurring compound that supports the brain's phospholipid synthesis, potentially enhancing neuronal repair and function. Researchers are excited about this treatment because it offers a novel mechanism of action that could not only slow cognitive decline but also improve overall brain health, which current options do not directly address.

Research shows that citicoline can help with brain health. Studies have found that citicoline improves memory and mental clarity, especially in older adults. In this trial, participants with Alzheimer's disease will receive either a citicoline supplement or a placebo. Treatments including citicoline have effectively boosted brain function. Citicoline is also safe, with studies showing it is well tolerated by Alzheimer's patients. While this study examines how citicoline might improve sleep, existing evidence supports its role in enhancing brain function.²⁴⁵⁶⁷