Pulsed Electromagnetic Field Treatment for Alzheimer's Disease
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial tests a new pulsed electromagnetic field treatment to determine its effectiveness in slowing the progression of Alzheimer's disease and related dementias. Participants will use a special device (ECHS AD Device) at home three times a day for 15 minutes over four months. The main goal is to observe changes in memory and thinking skills. The trial seeks individuals diagnosed with mild to moderate Alzheimer's or similar conditions, such as Lewy body or vascular dementia, who can follow the treatment routine. As an unphased trial, this study offers participants the chance to contribute to groundbreaking research that could lead to new treatment options for Alzheimer's and related dementias.
Will I have to stop taking my current medications?
If you are taking a cholinesterase inhibitor or memantine, you must have been on a stable dose for at least 60 days before the trial and continue that dose during the study. If you are taking anti-amyloid monoclonal antibodies, you must have stopped at least 3 months before the trial. The protocol does not specify other medication restrictions, but you cannot take medications that lower the seizure threshold.
What prior data suggests that this device is safe for Alzheimer's patients?
Research on the ECHS AD device shows it is generally well-tolerated. In past studies, people with Alzheimer's disease used this pulsed electromagnetic field treatment without major issues. The FDA has already approved some devices with similar technology for other conditions, supporting evidence of safety. However, while the device seems promising, detailed information about side effects specific to Alzheimer's treatment remains limited. Reports so far suggest it is safe, but further research could help confirm this.12345
Why are researchers excited about this trial?
Unlike the standard treatments for Alzheimer's disease, which often include medications like cholinesterase inhibitors and memantine aimed at managing symptoms, the ECHS AD device offers a unique approach. This treatment uses pulsed electromagnetic fields to potentially alter brain activity, aiming to target the disease's underlying mechanisms rather than just alleviate symptoms. Researchers are excited about the ECHS AD device because it represents a non-drug alternative that could open new avenues for managing Alzheimer's, with the potential for fewer side effects and novel therapeutic benefits.
What evidence suggests that the ECHS AD Device is effective for Alzheimer's Disease?
Research has shown that treatments using electromagnetic fields, such as the ECHS AD Device, can improve thinking and memory in people with Alzheimer's. Early studies suggest these treatments may slow the disease in mild to moderate cases. The ECHS AD Device, which trial participants will receive, uses pulsed electromagnetic fields believed to enhance brain cell function by boosting energy. While detailed data is still being gathered, early signs are promising for supporting brain health. This treatment offers hope for managing Alzheimer's symptoms more effectively.12345
Are You a Good Fit for This Trial?
This trial is for individuals with mild to moderate Alzheimer's Disease. Participants will use the ECHS AD device at home, three times a day for 15 minutes over a period of 120 days. The study requires follow-up for 9 months post-treatment.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive pulsed electromagnetic field treatment at home three times a day for 15 minutes over 120 days
Follow-up
Participants are monitored for safety and effectiveness after treatment
What Are the Treatments Tested in This Trial?
Interventions
- ECHS AD Device
Find a Clinic Near You
Who Is Running the Clinical Trial?
Herrick Medical LLC
Lead Sponsor
University of Miami
Collaborator