Neurotization for Breast Implant Complications

This trial explores a new technique called breast neurotization (also known as nerve grafting or nerve allograft reconstruction) to determine if it can help women regain nipple sensation after implant-based breast reconstruction. Researchers test this by performing the technique on one breast while leaving the other untouched to compare the results. It suits women undergoing bilateral nipple-sparing mastectomy (removal of breast tissue) who are receiving implants. As an unphased trial, this study provides a unique opportunity to contribute to innovative research that could improve post-surgical outcomes for future patients.

The trial protocol does not specify if you need to stop taking your current medications. However, if you have a history of diabetes with a high HgbA1c, auto-immune disease, or allergies to certain materials, you may not be eligible to participate.

The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your doctor.

Research shows that breast neurotization can help restore feeling after breast reconstruction. Studies indicate that patients who undergo this procedure often report improved sensation in their breasts, leading to greater comfort and a better quality of life.

However, some concerns exist. The procedure carries a risk of nerve damage, which might result in reduced feeling or ongoing nerve pain. Reports of these negative effects remain limited.

Unlike standard breast implant procedures that often leave the reconstructed breast without sensation, breast neurotization aims to restore feeling by connecting nerves to the nipple using nerve grafting techniques. This approach is unique because it targets nerve reconnection, potentially improving sensation and quality of life for patients after mastectomy. Researchers are excited about this technique because it offers hope for a more natural post-surgery experience, addressing a significant gap in current breast reconstruction methods.

Research has shown that breast neurotization, a procedure connecting nerves to restore sensation, may improve feeling for patients undergoing breast reconstruction. In this trial, one breast will be neurotized using nerve grafts, while the other will not undergo neurotization, serving as a control. Studies have found that nerve grafts during surgery lead to better sensation in the breast. For example, one study found that patients experienced noticeable improvements in sensation. Another review highlighted that these techniques can make the breast feel more natural after surgery, enhancing quality of life. While more research is needed, early findings suggest that breast neurotization might help restore nipple sensation.²⁶⁷⁸⁹