L-Theanine for Cancer
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial explores how L-theanine, a compound in green tea, can help cancer patients feel more relaxed and improve their mood after treatment. Researchers aim to determine the best dose and assess its effectiveness in reducing stress and enhancing mental well-being. Participants will take L-theanine once or twice daily for six weeks. Those who have been cancer-free and under medical surveillance for at least six months and often feel anxious might find this trial suitable. As an Early Phase 1 trial, this research focuses on understanding how L-theanine works in people, offering participants the chance to be among the first to benefit from this treatment.
Do I need to stop taking my current medications to join the trial?
The trial does not specify that you need to stop taking your current medications, but you must not have changed your psychiatric medications in the past 60 days. You also cannot use other alternative medicines, herbs, or high-dose vitamins unless correcting a deficiency.
Is there any evidence suggesting that L-theanine is likely to be safe for humans?
Research shows that L-theanine, a natural substance in green tea, is generally safe. Studies have found that L-theanine neither causes cancer nor affects reproduction. People have consumed it in tea for a long time without known safety issues. Further research suggests it can reduce stress and improve mood without serious side effects. Although this trial is in the early stages, existing evidence supports the safety of L-theanine in humans.12345
Why are researchers excited about this trial's treatment?
Researchers are excited about L-Theanine as a cancer treatment because it offers a unique approach compared to traditional therapies like chemotherapy and radiation. L-Theanine is derived from tea leaves and is known for its calming properties, but its potential in cancer treatment lies in its ability to enhance the effectiveness of existing treatments while potentially reducing side effects. Unlike conventional treatments that often come with a host of severe side effects, L-Theanine's natural origin might offer a more gentle alternative. Additionally, it can be administered orally, making it an accessible option for patients seeking less invasive treatment methods.
What evidence suggests that L-theanine might be an effective treatment for cancer patients' relaxation and mood?
Research has shown that L-theanine, a substance in green tea leaves, may help cancer patients feel more relaxed and improve their mood. L-theanine increases certain chemicals in the body that reduce stress and stabilize mood. Early studies suggest it can positively impact mental health and well-being. In lab tests, L-theanine also slowed the spread of cancer cells, particularly in prostate cancer. Although more research is needed, these early findings offer hope for its use in supporting the mental health of cancer patients. Participants in this trial will receive L-theanine either once or twice daily to evaluate its effects.23567
Who Is on the Research Team?
Erica Veguilla
Principal Investigator
City of Hope Medical Center
Are You a Good Fit for This Trial?
This trial is for cancer patients who are currently under surveillance, meaning they're being closely monitored but not actively receiving treatment. The study aims to see if L-theanine can help improve their relaxation and mood.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive L-theanine orally once daily or twice daily for 6 weeks
Follow-up
Participants are monitored for safety and effectiveness after treatment
What Are the Treatments Tested in This Trial?
Interventions
- L-Theanine
Find a Clinic Near You
Who Is Running the Clinical Trial?
City of Hope Medical Center
Lead Sponsor
National Cancer Institute (NCI)
Collaborator