Cognitive Behavioral Therapy for Smoking Cessation in HIV/AIDS

This trial tests Cognitive Behavioral Therapy (CBT) to help people with HIV quit smoking. The researchers aim to determine if this therapy can reduce anxiety and depression, which are common in people with HIV and can hinder smoking cessation. Participants will be divided into three groups: one will receive a specialized CBT called QUIT, another will receive a similar but different therapy, and the last group will receive their usual care plus nicotine patches. Individuals who smoke daily, have HIV, and wish to quit smoking may be suitable for this trial. As an unphased trial, this study offers a unique opportunity to explore new methods for improving mental health and aiding smoking cessation.

The trial information does not specify whether you need to stop taking your current medications. However, if you are currently receiving smoking cessation treatment, you may not be eligible to participate.

Research has shown that Cognitive Behavioral Therapy (CBT) is safe and well-tolerated for helping people with HIV quit smoking. In previous studies, participants handled this therapy well, with no major safety issues reported.

Early results suggest that CBT can significantly increase the chances of quitting smoking. This therapy helps by reducing anxiety and depression, which are common among smokers with HIV.

Although CBT is not a new medication, it has been tested in various groups, including those with HIV, to help people stop smoking. This background provides some confidence in its safety.

Cognitive Behavioral Therapy for smoking cessation in HIV/AIDS is unique because it combines a psychological approach with smoking cessation specifically tailored for people living with HIV. Most treatments for smoking cessation, like nicotine replacement therapy or prescription medications, focus on reducing withdrawal symptoms. However, this therapy aims to enhance distress tolerance and coping skills, which are crucial for individuals with HIV who often face additional stressors. Researchers are excited because it offers a holistic method, potentially leading to higher success rates in quitting smoking by addressing both the habit and the underlying stress factors.

Research has shown that Cognitive Behavioral Therapy (CBT) can help people with HIV quit smoking. In this trial, participants in the QUIT treatment arm will receive a CBT-based intervention for smoking cessation. A previous study found that individuals using the CBT approach were more successful at quitting smoking both in the short term and long term compared to those who received a brief treatment. This therapy reduces anxiety and depression, major challenges for smokers living with HIV. It addresses emotional issues such as excessive fear of anxiety, difficulty coping with emotional discomfort, and trouble experiencing pleasure. These early findings suggest that CBT could effectively help people with HIV stop smoking.¹³⁴⁶⁷