Dr. Mark I Boulos, MD, MSc
Claim this profileSunnybrook Health Sciences Centre
Studies Obstructive Sleep Apnea Syndrome
Studies Obstructive Sleep Apnea
5 reported clinical trials
8 drugs studied
Affiliated Hospitals
Clinical Trials Mark I Boulos, MD, MSc is currently running
Oropharyngeal Exercises
for Obstructive Sleep Apnea
The goal of this study is to determine whether a randomized controlled trial using oropharyngeal exercises to treat sleep apnea is feasible. Continuous positive airway pressure (CPAP) is the standard therapy for Obstructive sleep apnea (OSA), but it is poorly tolerated by many patients. Oropharyngeal exercises (OPEs) which are commonly used by speech-language pathologists to improve oro-motor strength, may serve as a promising alternative approach. The main questions this study aims to answer are: * Is it feasible to use an oropharyngeal exercise protocol in patients with sleep apnea? * Will oropharyngeal exercises improve sleep apnea severity, daytime sleepiness, sleep quality, mood, workplace performance, and quality of life Participants will be randomized into a supervised OPE intervention arm vs. unsupervised OPE intervention arm vs. sham treatment for a 10-week/5-day per week/two 20-minute session exercise protocol. The exercises will be administered via an app and the investigators will assess feasibility, as well as several sleep-related and oro-motor physiological outcomes before treatment, immediately post-treatment, and 4 weeks post-treatment. The investigators will use the results of this feasibility trial to inform the sample size needed for a larger clinical trial that will determine the efficacy of using oropharyngeal exercises to treat OSA.
Recruiting0 awards N/A3 criteria
Home Sleep Apnea Testing
for Cognitive Impairment
Obstructive sleep apnea (OSA), which causes abnormal pauses in breathing during sleep, is common in patients with vascular cognitive impairment (VCI) and Alzheimer's disease (AD), and exacerbates the cognitive deficits seen in these conditions. OSA is typically treated with continuous positive airway pressure (CPAP), which has been shown to improve cognition in VCI and slow cognitive decline in AD. Despite the need to identify OSA in patients with VCI/AD, these patients often do not undergo testing for OSA. One major barrier is that in-laboratory polysomnography (iPSG), the current standard for diagnosing OSA, is inconvenient for patients with VCI/AD who may be reliant on others for care or require familiar sleep environments. A convenient and cheaper alternative to iPSG is home sleep apnea testing (HSAT), which has been validated against iPSG to diagnose OSA and has proven feasible for use in VCI/AD. Our primary objective is to determine whether the use of HSAT is superior to iPSG in terms of the proportion of patients who complete sleep testing by 6 months post-randomization. We will also investigate cost-effectiveness, patient satisfaction, proportion of patients treated with CPAP, changes in cognition, mood, sleep-related and functional outcomes between HSAT and iPSG at 6 months.
Recruiting1 award N/A4 criteria
More about Mark I Boulos, MD, MSc
Clinical Trial Related2 years of experience running clinical trials · Led 5 trials as a Principal Investigator · 4 Active Clinical TrialsTreatments Mark I Boulos, MD, MSc has experience with
- Home Sleep Apnea Test
- In-laboratory Polysomnography
- Oropharyngeal Exercises
- Sham Exercises
- Clopidogrel
- Ticagrelor
Breakdown of trials Mark I Boulos, MD, MSc has run
Obstructive Sleep Apnea Syndrome
Obstructive Sleep Apnea
Lewy Body Dementia
Alzheimer's Disease
Other Doctors you might be interested in
Frequently asked questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the ‘trial drug’ — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
What does Mark I Boulos, MD, MSc specialize in?
Mark I Boulos, MD, MSc focuses on Obstructive Sleep Apnea Syndrome and Obstructive Sleep Apnea. In particular, much of their work with Obstructive Sleep Apnea Syndrome has involved treating patients, or patients who are undergoing treatment.
Is Mark I Boulos, MD, MSc currently recruiting for clinical trials?
Yes, Mark I Boulos, MD, MSc is currently recruiting for 4 clinical trials in Toronto Ontario. If you're interested in participating, you should apply.
Are there any treatments that Mark I Boulos, MD, MSc has studied deeply?
Yes, Mark I Boulos, MD, MSc has studied treatments such as Home Sleep Apnea Test, In-laboratory polysomnography, Oropharyngeal Exercises.
What is the best way to schedule an appointment with Mark I Boulos, MD, MSc?
Apply for one of the trials that Mark I Boulos, MD, MSc is conducting.
What is the office address of Mark I Boulos, MD, MSc?
The office of Mark I Boulos, MD, MSc is located at: Sunnybrook Health Sciences Centre, Toronto, Ontario M4N3M5 Canada. This is the address for their practice at the Sunnybrook Health Sciences Centre.
Is there any support for travel costs?
The coverage of travel expenses can vary greatly between different clinical trials. Please see more financial detail in the trials you’re interested to apply.
Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.