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We started Power when my dad was diagnosed with multiple myeloma, and I struggled to help him access the latest immunotherapy. Hopefully Power makes it simpler for you to explore promising new treatments, during what is probably a difficult time.

Bask
Bask GillCEO at Power
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      Why We Started Power

      We started Power when my dad was diagnosed with multiple myeloma, and I struggled to help him access the latest immunotherapy. Hopefully Power makes it simpler for you to explore promising new treatments, during what is probably a difficult time.

      Bask
      Bask GillCEO at Power
      Learn More About Trials
      How Do Clinical Trials Work?Are Clinical Trials Safe?What Can I Expect During a Clinical Trial?

      86 Osteoarthritis Trials near San Diego, CA

      Power is an online platform that helps thousands of Osteoarthritis patients discover FDA-reviewed trials every day. Every trial we feature meets safety and ethical standards, giving patients an easy way to discover promising new treatments in the research stage.

      Learn More About Power
      No Placebo
      Highly Paid
      Stay on Current Meds
      Pivotal Trials (Near Approval)
      Breakthrough Medication

      Amniotic Suspension Allograft for Knee Osteoarthritis

      San Diego, California
      This trial is testing if injecting ASA into the knee can help people with knee osteoarthritis feel better. The study will check pain levels, knee function, and safety over several months. ASA (Amniotic Suspension Allograft) has been shown to be an effective treatment for knee osteoarthritis in previous studies.
      Pivotal Trial (Near Approval)

      Trial Details

      Trial Status:Active Not Recruiting
      Trial Phase:Phase 3
      Age:19+
      Sex:Male

      Key Eligibility Criteria

      Disqualifiers:Knee Surgery, Infection, Substance Use, Others
      Must Not Be Taking:Anticoagulants, Immunosuppressives, Steroids

      474 Participants Needed

      RTX-GRT7039 Injections for Knee Osteoarthritis

      San Diego, California
      This trial uses knee injections called RTX-GRT7039 for patients with knee osteoarthritis who still have pain despite usual treatments. The injections aim to reduce knee pain, possibly by affecting pain pathways or inflammation.
      No Placebo Group
      Pivotal Trial (Near Approval)

      Trial Details

      Trial Status:Active Not Recruiting
      Trial Phase:Phase 3

      Key Eligibility Criteria

      Disqualifiers:Joint Replacement, Significant Trauma, Hip Osteoarthritis, Others

      930 Participants Needed

      TG-C for Osteoarthritis of the Knee

      San Diego, California
      This trial tests TG-C, an injection into the knee, for patients with moderate to severe osteoarthritis. It aims to reduce pain and improve knee function by potentially modifying the disease. TG-C has shown promise in previous studies for managing knee osteoarthritis.
      Pivotal Trial (Near Approval)

      Trial Details

      Trial Status:Active Not Recruiting
      Trial Phase:Phase 3
      Age:40+

      Key Eligibility Criteria

      Disqualifiers:Knee Disorders, Infections, Diabetes, Others
      Must Not Be Taking:NSAIDs, Steroids, Narcotics, Others

      535 Participants Needed

      Multiple Treatments for Chronic Pain

      San Diego, California
      This trial is testing different treatments for chronic pain in patients with knee osteoarthritis, chronic low back pain, and diabetic nerve pain. It aims to find effective ways to reduce their chronic pain.

      Trial Details

      Trial Status:Recruiting
      Trial Phase:Phase 2

      Key Eligibility Criteria

      Disqualifiers:Heart Block, Cancer, Fibromyalgia, Substance Use, Others

      10000 Participants Needed

      Hyalofast + Microfracture for Knee Cartilage Repair

      San Diego, California
      This trial tests a new treatment for knee cartilage damage using a special pad and concentrated bone marrow cells from the patient. It aims to help patients whose knee cartilage causes symptoms and may not respond to usual treatments. The pad supports the bone marrow cells to heal and regenerate the damaged area. Bone marrow concentrate (BMC) has shown promise in treating knee issues and cartilage repair due to its regenerative potential.
      No Placebo Group

      Trial Details

      Trial Status:Active Not Recruiting
      Trial Phase:Unphased
      Age:18 - 60

      Key Eligibility Criteria

      Disqualifiers:Advanced Osteoarthritis, Uncontrolled Diabetes, Rheumatoid Arthritis, Alcohol And Drug Abuse, Others
      Must Be Taking:NSAIDs, Acetaminophen

      200 Participants Needed

      Retatrutide for Obesity

      San Diego, California
      The purpose of this study is to evaluate the efficacy and safety of retatrutide in participants who have obesity or overweight (J1I-MC-GZBJ master protocol) including subsets of participants who have knee osteoarthritis (OA) (J1I-MC-GOA1) or who have obstructive sleep apnea (OSA) (J1I-MC-GSA1). This study will last about 89 weeks and will include up to 24 visits. Addendum (2) is optional and available to approximately 500 participants to continue treatment with retatrutide for up to an additional 24 weeks.
      Pivotal Trial (Near Approval)

      Trial Details

      Trial Status:Active Not Recruiting
      Trial Phase:Phase 3

      Key Eligibility Criteria

      Disqualifiers:Diabetes, Thyroid Carcinoma, Pancreatitis, Others
      Must Not Be Taking:Weight Loss Drugs, Stimulants, Hypnotics, Others

      2300 Participants Needed

      Retatrutide for Obesity

      San Diego, California
      This trial is testing a weekly medication called retatrutide. It aims to help people who are overweight or obese and have knee osteoarthritis. The study will last over a year to see if the medication is safe and effective.
      Pivotal Trial (Near Approval)

      Trial Details

      Trial Status:Active Not Recruiting
      Trial Phase:Phase 3

      Key Eligibility Criteria

      Disqualifiers:Steroid Injections, Joint Disease, Diabetes, Others
      Must Not Be Taking:Weight Loss Drugs

      405 Participants Needed

      Fat Cell Injections for Knee Osteoarthritis

      La Mesa, California
      This trial is testing an injection of a patient's own processed fat tissue to treat knee pain and improve function in people with moderate knee osteoarthritis. The fat tissue is thought to help by cushioning the joint and possibly aiding in healing. This treatment has been studied for its potential to improve pain and function in patients with knee osteoarthritis.
      No Placebo Group
      Pivotal Trial (Near Approval)

      Trial Details

      Trial Status:Active Not Recruiting
      Trial Phase:Phase 3

      Key Eligibility Criteria

      Disqualifiers:Rheumatoid Arthritis, Infection, Obesity, Others
      Must Not Be Taking:Corticosteroids, Anti-coagulants

      173 Participants Needed

      Amniotic Suspension Allograft for Osteoarthritis

      La Mesa, California
      This trial is testing a new treatment called ASA, which is injected directly into the knee joint. It aims to help patients with knee osteoarthritis by reducing pain and improving joint function. The study will compare the effects of ASA over several months.
      Pivotal Trial (Near Approval)

      Trial Details

      Trial Status:Active Not Recruiting
      Trial Phase:Phase 3

      Key Eligibility Criteria

      Disqualifiers:Knee Surgery, Immunosuppressive Therapy, Others
      Must Not Be Taking:NSAIDs, Anticoagulants, Corticosteroids, Others

      474 Participants Needed

      Stem Cell Treatment for Knee Osteoarthritis

      La Mesa, California
      This trial is testing a new treatment that uses cells from a patient's own fat to help repair knee damage in people with knee osteoarthritis. The cells are injected into the knee to reduce pain and improve joint function. This type of therapy has been increasingly studied and used for treating knee osteoarthritis due to its potential to reduce pain and improve joint function.
      Pivotal Trial (Near Approval)

      Trial Details

      Trial Status:Recruiting
      Trial Phase:Phase 2, 3

      Key Eligibility Criteria

      Disqualifiers:BMI > 35, Cancer, Heart Diseases, Autoimmune Diseases, Inflammatory Joint Disorders, Others
      Must Not Be Taking:Anti-inflammatories, Oral Steroids

      140 Participants Needed

      TG-C for Knee Osteoarthritis

      San Diego, California
      This trial tests TG-C, an injection into the knee, for people with moderate to severe knee osteoarthritis. It aims to see if TG-C can reduce pain and improve knee function by potentially altering the disease. The study will monitor patients for safety and effectiveness over time. TG-C has been previously studied for its potential to improve knee joint function and reduce pain in osteoarthritis patients.
      Pivotal Trial (Near Approval)

      Trial Details

      Trial Status:Active Not Recruiting
      Trial Phase:Phase 3
      Age:40+

      Key Eligibility Criteria

      Disqualifiers:Rheumatoid Arthritis, Diabetes, Cancer, Others
      Must Not Be Taking:NSAIDs, Steroids, Biologics, Narcotics

      531 Participants Needed

      Gene Therapy for Knee Osteoarthritis

      San Diego, California
      This trial is testing a new treatment for people with painful knee osteoarthritis. The treatment uses a special virus to deliver a helpful gene directly into the knee. Researchers want to see if this single injection is safe and well-tolerated.

      Trial Details

      Trial Status:Active Not Recruiting
      Trial Phase:Phase 1
      Age:40 - 75

      Key Eligibility Criteria

      Disqualifiers:Inflammatory Arthritis, Joint Degeneration, Surgery, Others

      67 Participants Needed

      Anti-inflammatory Diet for Osteoarthritis

      San Diego, California
      In a previous exploratory study, the investigators observed an effect on disease activity outcomes of anti-inflammatory diet. The investigators also observed change in microbiome and circulating metabolites. The current study will determine whether or not the addition of anti-inflammatory diet improves the clinical outcomes in participants with Osteoarthritis, and the role of microbiome and circulating metabolites.
      No Placebo Group

      Trial Details

      Trial Status:Recruiting
      Trial Phase:Unphased

      Key Eligibility Criteria

      Disqualifiers:Knee Surgery, Rheumatoid Arthritis, Others
      Must Not Be Taking:Corticosteroids, Fish Oils

      72 Participants Needed

      Anti-inflammatory Diet for Knee Osteoarthritis

      La Jolla, California
      To study the effect of anti-inflammatory diet on clinical and biological outcomes in patients with knee osteoarthritis
      No Placebo Group

      Trial Details

      Trial Status:Recruiting
      Trial Phase:Unphased

      Key Eligibility Criteria

      Disqualifiers:Food Allergies, Pregnancy

      30 Participants Needed

      Episealer Knee System vs Microfracture Surgery for Osteoarthritis

      La Mesa, California
      This trial is testing a knee implant called the Episealer Knee System on patients with specific knee damage causing pain or disability. The implants aim to repair the damaged areas, improving knee function and reducing pain.

      Trial Details

      Trial Status:Active Not Recruiting
      Trial Phase:Unphased
      Age:30 - 70

      Key Eligibility Criteria

      Disqualifiers:Obesity, Osteoporosis, Rheumatoid Arthritis, Others
      Must Not Be Taking:Corticosteroids, Immunosuppressants, Immunostimulants, Others

      13 Participants Needed

      Pentosan Polysulfate Sodium Injections for Osteoarthritis

      Spring Valley, California
      This trial tests if a new treatment can reduce pain and improve function in people with knee osteoarthritis. The medication aims to reduce inflammation and help repair knee joint damage.
      Pivotal Trial (Near Approval)

      Trial Details

      Trial Status:Active Not Recruiting

      Key Eligibility Criteria

      Disqualifiers:Not Listed

      602 Participants Needed

      Non-Surgical Interventions for Knee Osteoarthritis

      San Diego, California
      There is an urgent public health need to reduce reliance on opioids for effective long-term pain management, particularly in knee osteoarthritis (KOA). This effectiveness trial will compare commonly recommended treatments to reduce pain and functional limitations in KOA.These results will lead to improved patient selection for treatment and inform evidence based guidelines by offering well-tested, effective, non-surgical alternatives.
      No Placebo Group
      Pivotal Trial (Near Approval)

      Trial Details

      Trial Status:Active Not Recruiting

      Key Eligibility Criteria

      Disqualifiers:Not Listed

      1800 Participants Needed

      TTAX03 Injection for Knee Osteoarthritis

      La Mesa, California
      This trial tests if a single injection of TTAX03 in saltwater can improve knee conditions better than just saltwater. It targets patients needing knee injections and checks their response over a few months.

      Trial Details

      Trial Status:Active Not Recruiting
      Age:35 - 85

      Key Eligibility Criteria

      Disqualifiers:Not Listed

      90 Participants Needed

      Enekinragene Inzadenovec for Knee Arthritis

      La Mesa, California
      The goal of this clinical trial is to learn if a single knee injection of different doses (Dose A and Dose B) of an investigation product PCRX-201, following steroid pretreatment, is safe and tolerable in male of female patients 45 to 80 years old with osteoarthritis of the knee. It will also learn how the body reacts to the PCRX-201 injection and how effective the treatment is. Researchers will compare Dose A and Dose B of PCRX-201 versus placebo from Week 1 through Week 52 to assess adverse events. Researchers will also explore how PCRX-201 may impact knee pain and joint function over time. Participants will be asked to * Visit the clinic for pretreatment and drug administration * Visit the clinic for checkups and tests: 1. Screening through Week 52: intially weekly, bi-weekly, later monthly 2. Week 53 through Week 260 (Year 5): 8 visits throughout the period

      Trial Details

      Trial Status:Recruiting
      Trial Phase:Phase 2
      Age:45 - 80

      Key Eligibility Criteria

      Disqualifiers:Autoimmune Disorders, Infections, Unstable Knee, Others
      Must Be Taking:Steroids

      135 Participants Needed

      ZILRETTA for Shoulder Osteoarthritis

      La Mesa, California
      Primary Objective: To assess the efficacy of ZILRETTA on pain following an intra-articular (IA) injection in subjects with glenohumeral osteoarthritis (OA) relative to normal saline placebo Secondary Objective: * To assess the efficacy of ZILRETTA on pain following an IA injection in subjects with glenohumeral OA relative to triamcinolone acetonide injectable suspension, and normal saline placebo * To assess the safety of ZILRETTA in subjects with glenohumeral OA relative to normal saline placebo
      Pivotal Trial (Near Approval)

      Trial Details

      Trial Status:Recruiting
      Trial Phase:Phase 3
      Age:50 - 80

      Key Eligibility Criteria

      Disqualifiers:Symptomatic Arthritis, Rotator Cuff Pathology, Chronic Shoulder Pain, Others
      Must Not Be Taking:Opioids, Analgesics, THC/CBD, SSRIs/SNRIs

      150 Participants Needed

      Why Other Patients Applied

      "I am an active athlete who is not ready or willing to stop my activities because of knee pain at 42. I have tried cortisone shots and found they only temporary mask the issue, or even cause more problems later. That's why I started researching medical studies."

      GM
      Arthritis PatientAge: 44

      "I’m allergic to so many standard arthritis drugs, so I've been researching some of the newest ones still in the research phase. I'm hoping to find out if I'd be a good match—it would be great to find something that works (and, if not, at least contribute to the cause)."

      TJ
      Arthritis PatientAge: 79

      "I’ve tried several meds without too much relief. Injections only work on my right knee but not much on the left knee. My pain is nearly unbearable at this point. Hoping to learn about what promising drugs exist in trials."

      YV
      Arthritis PatientAge: 61

      "My orthopedist recommended a half replacement of my right knee. I have had both hips replaced. Currently have arthritis in knee, shoulder, and thumb. I want to avoid surgery, and I'm open-minded about trying a trial before using surgery as a last resort."

      HZ
      Arthritis PatientAge: 78

      "I have been struggling with severe knee pain since my service in the military. I am only 52! I miss doing the things I used to do."

      NA
      Arthritis PatientAge: 55
      Match to a Osteoarthritis Trial

      MFat vs Corticosteroid Injection for Knee Osteoarthritis

      Encinitas, California
      This trial is testing a new treatment where a patient's own fat is processed and injected into their knee to help with pain and function in people with moderate knee osteoarthritis. The goal is to see if this method works better by reducing inflammation and promoting healing. This approach has shown promising results in reducing pain and improving function.
      No Placebo Group
      Pivotal Trial (Near Approval)

      Trial Details

      Trial Status:Active Not Recruiting
      Trial Phase:Phase 3

      Key Eligibility Criteria

      Disqualifiers:Not Listed

      173 Participants Needed

      TPX-100 for Knee Arthritis

      Encinitas, California
      53-Week Study Evaluating the Safety and Efficacy of Intra-articular (IA) Injections of TPX-100 vs Placebo in Subjects with Mild to Severe Tibio-Femoral Osteoarthritis of the Knee

      Trial Details

      Trial Status:Recruiting
      Trial Phase:Phase 2
      Age:50 - 80

      Key Eligibility Criteria

      Disqualifiers:Rheumatoid Arthritis, Fibromyalgia, Others
      Must Not Be Taking:Systemic Steroids, Paclitaxel

      270 Participants Needed

      MISHA Knee System for Osteoarthritis

      Oceanside, California
      Prospective, multicenter, two-arm, 2:1 randomized controlled trial (RCT) comparing the benefits in subjects with medial knee osteoarthritis who are treated with either the MISHA Knee System or with non-surgical treatment. This is the first randomized head-to-head study comparing outcomes from subjects treated with the MISHA Knee System.
      No Placebo Group

      Trial Details

      Trial Status:Recruiting
      Trial Phase:Unphased

      Key Eligibility Criteria

      Disqualifiers:Poor Bone Quality, Ligamentous Instability, Inflammatory Joint Disease, Others

      100 Participants Needed

      mymobility App + Apple Watch for Osteoarthritis Recovery

      Irvine, California
      This trial is testing if a smartphone app and fitness trackers can help patients recover better after knee or hip replacement surgeries compared to traditional physical therapy.
      No Placebo Group

      Trial Details

      Trial Status:Active Not Recruiting
      Trial Phase:Unphased

      Key Eligibility Criteria

      Disqualifiers:Alcohol Or Drug Abuse, Inflammatory Arthropathies, Protected Population, Others

      10500 Participants Needed

      SyntrFuge™-Processed Adipose Tissue for Knee Osteoarthritis

      Irvine, California
      This is an multi-center study with the aim of evaluating the efficacy of adipose tissue processed with the SyntrFuge™ system in Orthopedic Surgery, specifically Knee Osteoarthritis. Patients will be enrolled to the treatment group with adipose tissue processed with the SyntrFuge™ system followed by an injection of autologous microsized adipose tissue in the treatment sites or Standard of Care.
      No Placebo Group

      Trial Details

      Trial Status:Recruiting
      Trial Phase:Unphased

      Key Eligibility Criteria

      Disqualifiers:Osteonecrosis, Gout, Inflammatory Arthritis, Others
      Must Not Be Taking:Anticoagulants, NSAIDs, Corticosteroids, Others

      176 Participants Needed

      Shoulder Arthroplasty for Shoulder Conditions

      Irvine, California
      The objectives of this study are to confirm the safety, performance, and clinical benefits of Zimmer Biomet Shoulder Arthroplasty Systems and its instrumentation in primary or revision shoulder arthroplasty. These objectives will be assessed using standard scoring systems, radiographic evidence, and adverse event records. Safety of the system will be assessed by monitoring the frequency an incidence of adverse events.
      No Placebo Group

      Trial Details

      Trial Status:Recruiting
      Trial Phase:Unphased
      Age:20+

      Key Eligibility Criteria

      Disqualifiers:Pregnancy, Osteoporosis, Neuromuscular Disease, Others

      584 Participants Needed

      Orforglipron for Obesity

      Huntington Beach, California
      The GZPT master protocol will support two independent studies, J2A-MC-GZT1 and J2A-MC-GZT2. Each study will see how well and safely orforglipron works in people with obesity or overweight who have osteoarthritis (OA) of the knee with pain. Participation in the study will last about 74 weeks.
      Pivotal Trial (Near Approval)

      Trial Details

      Trial Status:Recruiting
      Trial Phase:Phase 3

      Key Eligibility Criteria

      Disqualifiers:Diabetes, Recent Heart Condition, Others
      Must Not Be Taking:GLP-1 Receptor Agonists

      800 Participants Needed

      Infection Prophylaxis with Vancomycin + Povidone Iodine for Post-Surgical Joint Infections

      Rancho Mirage, California
      This is a prospective, randomized, controlled, open label, parallel four-arm design, multi-center study to compare different intraoperative interventions in the prevention of acute PJI development.
      No Placebo Group

      Trial Details

      Trial Status:Active Not Recruiting
      Trial Phase:Phase 1

      Key Eligibility Criteria

      Disqualifiers:Pregnancy, Psychiatric Disorder, Severe Dementia, Others

      2129 Participants Needed

      Total Knee Replacement for Osteoarthritis

      Rancho Mirage, California
      The primary objective of this study is to obtain long-term implant survivorship (out to 10 years) and to assess clinical, patient-reported outcome measures, and radiographic data for the commercially available Physica system. For ancillary arm, from baseline to 5-year follow-up.
      No Placebo Group

      Trial Details

      Trial Status:Recruiting
      Trial Phase:Unphased
      Age:22+

      Key Eligibility Criteria

      Disqualifiers:Infections, Bone Loss, Neurological Disorders, Others

      800 Participants Needed

      Total Knee Replacement for Osteoarthritis

      Orange, California
      This post-marketing investigation will evaluate the long term (up to 15 years) survivorship of the Attune Primary Knee Prosthesis in patients with non-inflammatory degenerative joint disease. Data from Subjects who receive one of four knee configurations will be pooled to establish a contemporary dataset.
      No Placebo Group

      Trial Details

      Trial Status:Active Not Recruiting
      Trial Phase:Unphased
      Age:22 - 75

      Key Eligibility Criteria

      Disqualifiers:Pregnancy, Amputation, Inflammatory Arthritis, Others
      Must Not Be Taking:Fibromyalgia Medications

      1542 Participants Needed

      123

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      Why We Started Power

      We started Power when my dad was diagnosed with multiple myeloma, and I struggled to help him access the latest immunotherapy. Hopefully Power makes it simpler for you to explore promising new treatments, during what is probably a difficult time.

      Bask
      Bask GillCEO at Power
      Learn More About Trials
      How Do Clinical Trials Work?Are Clinical Trials Safe?What Can I Expect During a Clinical Trial?
      Match to a Trial
      Match to a Trial

      Frequently Asked Questions

      How much do Osteoarthritis clinical trials in San Diego, CA pay?

      Each trial will compensate patients a different amount, but $50-100 for each visit is a fairly common range for Phase 2–4 trials (Phase 1 trials often pay substantially more). Further, most trials will cover the costs of a travel to-and-from the clinic.

      How do Osteoarthritis clinical trials in San Diego, CA work?

      After a researcher reviews your profile, they may choose to invite you in to a screening appointment, where they'll determine if you meet 100% of the eligibility requirements. If you do, you'll be sorted into one of the treatment groups, and receive your study drug. For some trials, there is a chance you'll receive a placebo. Across Osteoarthritis trials in San Diego, CA 30% of clinical trials have a placebo. Typically, you'll be required to check-in with the clinic every month or so. The average trial length in San Diego, CA for Osteoarthritis is 12 months.

      How do I participate in a study as a "healthy volunteer"?

      Not all studies recruit healthy volunteers: usually, Phase 1 studies do. Participating as a healthy volunteer means you will go to a research facility in San Diego, CA several times over a few days or weeks to receive a dose of either the test treatment or a "placebo," which is a harmless substance that helps researchers compare results. You will have routine tests during these visits, and you'll be compensated for your time and travel, with the number of appointments and details varying by study.

      What does the "phase" of a clinical trial mean?

      The phase of a trial reveals what stage the drug is in to get approval for a specific condition. Phase 1 trials are the trials to collect safety data in humans. Phase 2 trials are those where the drug has some data showing safety in humans, but where further human data is needed on drug effectiveness. Phase 3 trials are in the final step before approval. The drug already has data showing both safety and effectiveness. As a general rule, Phase 3 trials are more promising than Phase 2, and Phase 2 trials are more promising than phase 1.

      Do I need to be insured to participate in a Osteoarthritis medical study in San Diego, CA?

      Clinical trials are almost always free to participants, and so do not require insurance. The only exception here are trials focused on cancer, because only a small part of the typical treatment plan is actually experimental. For these cancer trials, participants typically need insurance to cover all the non-experimental components.

      What are the newest Osteoarthritis clinical trials in San Diego, CA?

      Most recently, we added Platelet Rich Plasma for Musculoskeletal Conditions, Surgical Navigation System for Osteoarthritis and Orforglipron for Obesity to the Power online platform.

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